Using one-molecule optical and AFM imaging and pressure-spectroscopy strategies, we look for to unravel the mechanistic elements of the composition and dynamics of chromosomes. Our exploration passions consist of:
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Dynamics of initiation, termination and reinitiation of DNA translocation by the motor protein EcoR124I
Our perform was speedily adopted up by Some others, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 revealed their results on transistors made out of solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt in excess of het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft fulfilled veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
Within the many years following these discoveries, my research pursuits shifted to biophysics and nanobiology, And that i became much less involved in the event of nanotube electronics. The main focus of many scientists in the sector also shifted to graphene (where, funnily more than enough, the 1st graphene ribbons ended up referred to as ‘nanotubes that are Minimize open up along their size’) after the discovery of The 2-dimensional material in 2004.
Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis from DNA supercoiling scientific tests of nucleosomes and DNA repair service proteins to DNA translocation as a result of nanopores. Not too long ago his exploration has focused on learning cell division with bacteria on chip, although his supreme fascination is from the way of noticing artificial cells.
Atomic power microscopy displays that vaccinia topoisomerase IB generates filaments on DNA inside of a cooperative manner
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At the moment, we also realized that it ought to be achievable to make use of only one semiconducting carbon nanotube for making a transistor — and we set out to really make it. We stretched specific semiconducting nanotubes across metallic electrodes and made use of the underlying silicon substrate as a gate electrode, developing the basic a few-terminal layout of the discipline-effect transistor (Fig.
Considering the fact that 2000 he moved to single-molecule biophysics and nanobiology, with exploration from research of DNA loop extrusion and supercoiling to DNA translocation by nanopores. More just lately his investigate has focused on finding out chromatin composition and cell division with microorganisms on chip, though he can also be aiming to finally Develop synthetic cells from The underside up.
Nanoscientist Cees Dekker is surely an amiable and flamboyant man who seems Substantially young compared to the sixty two decades he essentially is – trendy glasses, psychedelic shirt, partaking smile – although not a single to waste time. He usually takes his time, but not cees dekker more than needed.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever design and style in 2005. (nl)